8th May
Topic: Technology and Application
- Current developments in upscaling
- Comparison of various systems
- Size relevance for gene transfer
- Drug delivery and targeting
- First results of in-vitro studies
- Future clinical applications
9.00 Registration, Coffee and Tee
9.45 Welcome Note and Introduction
Uwe Lück, IHK Ostwestfalen zu Bielefeld
Martin Schleef, PlasmidFactory GmbH & Co. KG
10.00
Peter Mayrhofer,
Mayrhofer & Jechlinger OEG, Wien and
Marco Schmeer,
PlasmidFactory GmbH & Co. KG, Bielefeld
Large scale production of minicircle DNA becomes reality
10.30
Eberhard Neumann,
Universität Bielefeld:
Fundamentals of Minicircle-DNA transfer by membrane electorporation
11.00 Coffee Break
11.15
Jürgen Bode,
Helmholtz Zentrum für Infektionsforschung, Braunschweig
Replicating nonviral minicircles: Novel Tools for the predictable transgenesis of dividing cells
11.45
Daniel Scherman, Université Paris:
Triple Helix Affinity Chromatography Purification of Plasmid DNA
12.15 Lunch Break
13.30
Christiane Juhls,
MOLOGEN AG, Berlin:
Minimalistic Linear Gene Expression Constructs: MIDGE Vectors
14.00
Jürgen Mairhofer,
Universität für Bodenkultur Wien:
Antibiotic-free Selection System for the Manufacturing of Minimized Plasmids
14.30
Wolfgang Walther, Max-Delbrück-Centrum für Molekulare Medizin, Berlin:
Minicircle technology for improved nonviral gene transfer
15.00 Coffe Break
15.30
Frank Jacobs, Center for Melecular & Vascular Biology, Leuven
Direct Comparison of Hepatocyte-specific Expression cassettes Following Adenoviral and Non-viral Hydrodynamic Gene Transfer
16.00
Manfred Gossen,
Max-Delbrück-Centrum für Molekulare Medizin, Berlin:
Functional autonomy of transgenic transcription units
16.30 Summary and Outlook
16.45 End of Scientific Programme
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